Overview
This year our two annual courses will be linked to provide a two-day course of lectures and practical experience in liver pathology. Delegates have the option of attending either or both of the days.
 
The first day will provide a practical diagnostic approach to reporting medical liver biopsies, focusing on the importance of clinico-pathological correlation in assessing common patterns of liver damage. Recommended for senior trainees in Pathology and Hepatology and consultant histopathologists and gastroenterologists who are regularly involved in liver biopsy assessment (without necessarily working in a Liver Unit).

The second day will be a slide-based practical workshop for histopathologists which will cover the main types of medical liver disease as well as a range of focal liver lesions.

 

Day 1 - Liver Biopsy in the Assessment of Medical Liver Disease

Thursday 5th March 2020 (5CPD Points)
This course, organised by Professor Stefan Hübscher, will be delivered for the tenth time in 2020. Presentations by hepatologists and histopathologists cover the investigation of medical liver diseases.
The course provides a practical diagnostic approach to reporting medical liver biopsies, focusing on the importance of clinico-pathological correlation in assessing common patterns of liver damage.

 

Day 2 - Histopathology Workshop -  Liver Pathology

Friday 6th March 2020 (5CPD Points)
This slide-based practical workshop for histopathologists is devised for consultants working outside specialist liver centres, and trainees in stage C or D who have an interest in liver pathology.  It is designed to complement the annual course; ‘Liver biopsy in the assessment of medical liver disease’, but also works as a stand-alone course.  

Learning Outcomes:
At the end of the session individuals should:

  • Have pre-viewed a range of liver cases, as virtual slides pre-meeting, and also available using iPads during the meeting.
  • Be confident in recognising common patterns of medical liver disease in liver biopsies 
  • Understand the role of different special stains in medical liver biopsies
  • Have gained an understanding of the pathological assessment of focal liver lesions 

The UK Liver Pathology group was founded in 2016 to promote excellence in liver histopathology services in the UK and Ireland, across all levels of specialisation, through professional collaboration in education, quality assurance and research. We aim to provide a range of training and CPD materials and events, suitable for trainees and consultants in specialist and generalist settings.This course is being run for the 6th time; it was first held as a BDIAP histopathology workshop in March 2014. Due to the variation in provision of liver services, there is limited exposure to liver histopathology in some training programmes. 
This course would be particularly useful for trainees who are looking for a concise all-round practical learning opportunity in liver pathology. Delegates have the option of attending either or both of the days.

Digital Slides
Please note: During the meeting, digital slides can be viewed using iPads (Aperio ePathViewer). This will be the second time we have used digital slides for this course instead of microscopes, this was very well received last year. Delegates can bring their own iPad or pay for the iPads that will be hired. 

 

Programme 5th & 6th March 2020

Liver Biopsy in the Assessment of Medical Liver Disease
Thursday 5th March 2020

09.20   Registration and Coffee 
09.50   Welcome and Introduction - Professor Stefan Hübscher, Birmingham 
                Clinical Indications and General Approaches to Liver Biopsy Interpretation
10.00   Patterns of abnormal LFTs and their differential diagnosis - Professor Matthew                                  Cramp, Plymouth 
10.25   Indications for liver biopsy in investigating common medical liver diseases – what                           information is required from a liver biopsy report? - Dr Steve Ryder, Nottingham
10.50   Coffee  
11.20   How to handle liver biopsy specimens – specimen fixation, processing and staining                          methods - Dr Alberto Quaglia, Kings College  Hospital, London
11.45   Basic patterns of liver damage – what information can a liver biopsy provide and what                   clinical information does the pathologist need? - Professor Rob Goldin, Imperial                            College, London
12.10   Lunch
                Clinico-Pathological Assessment of Common Medical Liver Diseases
13.10   Fatty liver disease – Dr Judy Wyatt & Dr Ian Rowe, Leeds
13.55   Chronic biliary disease – Dr Susan Davies & Dr Will Gelson, Cambridge 
14.40   Tea
15.10   Chronic hepatitis – viral and autoimmune – Dr Chris Bellamy & Dr Andrew Bathgate,                   Edinburgh 
15.55   Acute hepatitis, including acute liver failure – Professor Stefan Hübscher & Dr Palak                    Trivedi, Birmingham
16.40   Panel Discussion, Questions and Answers. Concluding remarks and close

Histopathology Workshop -  Liver Pathology
Friday 6th March 2020

9.00     Registration and Coffee
                 Viewing of scanned cases as a refresher prior to the meeting. The course teachers will be                             available to discuss cases.
09.50   Welcome and Introduction – Dr Judy Wyatt, Leeds
10.00   Slides Seminar: Medical liver biopsies - Dr Judy Wyatt  
11.30   Coffee and slide viewing
12.00   Slide Seminar: medical liver biopsies cases, 1-7 - Dr Susan Davies
12.45   Lunch
13.30   Slide Seminar: medical liver biopsies, cases 8-13 - Dr Susan Davies 
14.15   Tea and slide viewing
14.45   Slide Seminar: Focal Liver Lesions (10 cases) - Professor Stefan Hubscher -
16.15   Concluding remarks and close
Registration Fees/iPad Hire

Online Rates - One/two day fees 
RCPath members £202 (1 day fee) or £370 (2 day fee)
Concessions £108 (1 day fee) or £192 (2 day fee) - Concessions include trainees, BMS, non-consultant Clinical Scientists, retired & nurses
Non-members £280 (1 day fee) or £430 (2 day fee)

Offline Rates - (payments via cheque/invoice or on the day payments)
RCPath members £238 (1 day fee) or £405 (2 day fee)
Concessions £142 (1 day fee) or £225 (2 day fee) - Concessions include trainees, BMS, non-consultant Clinical Scientists, retired & nurses
Non-members £312 (1 day fee) or £461 (2 day fee)

Please note that an administrative charge of £20.00 will be made on all cancellations and the total registration fee is forfeited if cancelled one working week before the event.

Location

Both days are hosted by the Royal College of Pathologists; at 6 Alie Street, London E1 8QT.

Speakers

Liver Biopsy in the Assessment of Medical Liver Disease and Liver Pathology

  • Dr Chris Bellamy

    Reader in liver and renal pathology at the University of Edinburgh, with a particular interest in clinical transplant pathology. I’m also involved in developing the new year 1 and 2 undergraduate medical curriculum, in particular the molecular genetics/infection/inflammation and cancer aspects. My research currently covers combining multiplex immunofluorescence with spectral analysis and  unsupervised machine learning algorithms to better phenotype immune infiltrates in clinical biopsy material. We have projects running in transplantation, ANCA vasculitis and phenotyping immune infiltrates of bladder cancer. 

  • Dr Will Gelson

    Dr Will Gelson is a consultant hepatologist at Addenbrooke’s Hospital in Cambridge. During his training he completed an MD in liver transplantation. Clinical interests include viral hepatitis, liver transplantation and biliary disease. He is clinical lead for the Eastern Hepatitis Network and secretary of the British Viral Hepatitis Group.

  • Professor Rob Goldin

    I am Professor of Gastro-intestinal and Liver Pathology at Imperial College and  Clinical Lead for Gastro-intestinal pathology in the North-West London Pathology Trust.  I also work  at the Ludwig Institute for Cancer Research in Oxford.  My interests are in clinical and experimental aspects hepato-biliary and gastro-intestinal disease. I am,  especially,  focused on liver cancer, fatty liver hepatitis and gastro-intestinal malignancy.  As part of this, I have an extensive experience of phenotyping mouse models of disease.  I am particularly interested in developing new approaches to obtaining information from tissue using computational pathology, metabonomic and other imaging techniques.  

  • Professor Stefan G. Hübscher

    Stefan Hübscher is Leith Professor and Professor of Hepatic Pathology at the  University of Birmingham and Consultant Histopathologist at the Queen Elizabeth Hospital, Birmingham UK.

    Clinical, teaching and research interests are mainly focused on liver pathology, including hepatic neoplasia and liver transplant pathology. Published works include >200 scientific papers in peer-reviewed journals, >50 review articles and 28 book chapters. Co-editor of MacSween’s Pathology of the Liver, 7th Edition, published in August 2017.

  • Dr Ian Rowe

    Ian is a Senior Lecturer at the University of Leeds and Honorary Consultant Hepatologist at the Liver Unit at St James’s University Hospital.  He did research training in Birmingham and was awarded an MRC Clinical Research Training Fellowship.  This, together with an NIHR Clinical Lectureship, gave him the independence to pursue clinical trial and applied health research evaluating the quality of evidence supporting interventions for patients with liver disease.  His position in Leeds is based within the MRC funded Leeds Institute for Data Analytics and his research is now focused on decision-making in the management of nonalcoholic fatty liver disease and the outcomes of patients with cirrhosis and hepatocellular carcinoma.

  • Dr Palak Trivedi

    Dr Trivedi is a Clinician Scientist at the National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre (BRC), based at the University of Birmingham. Dr. Trivedi is a Consultant Hepatologist who has devoted his clinical and research career to studying chronic autoimmune and cholestatic liver disease. He completed his PhD in Liver Immunology in 2015; during which time his work on risk stratification in PBC was ranked the top scoring clinical research abstract at the EASL international liver congress. Dr. Trivedi went on to receive the young investigator of the year award in 2017, was recipient of the Andy Burroughs’ prize for best Hepatology research at the British Association for Study of the Liver (BASL), and won the Elwyn Elias prize for research into PSC and liver transplantation the same year. He joined faculty at the Birmingham Liver Unit in 2018, with 50% protected research time, and currently leads the PBC and PSC clinical research programme. Dr. Trivedi is Chief Investigator for the UK-PSC consortium, and was elected chair of the British Association for Study of the Liver Special Interest Group (BASL SIG) for immune-mediated liver disease in 2018. He has over 60 articles on PubMed in the last 5 years, 45 in the last five years alone; with 35 as original articles, 18 as invited reviews or editorials, and 37 as first or lead author. The overarching themes of his research are in the role of gut-liver immunity, modelling the natural history of PBC and PSC, generating real-world clinical outcome data, and risk stratification pre- and post-transplantation.