Advances in malaria prevention

October 2025

New approaches to malaria prevention have promising results.

Despite significant control efforts since the turn of the millennium, globally there are still 263 million cases of malaria per year, with an annual total of approximately 600,000 deaths. Of these, 74% are in children under 5.1 New approaches to malaria control, complementing the use of insecticide-treated nets and current first-line therapies, are sorely needed to decrease this significant morbidity and mortality burden. This article reviews the status of malaria vaccination and other novel approaches to prevention and treatment.