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The Sampson equation for LDL-cholesterol estimation: Clinical biochemistry impact and rationale for adoption – an introductory guide for trainees

April 2026

What advantages does Sampson’s equation have over traditional methods for cardiovascular risk assessment?

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In this article, Zeenath Thaneefa Mohamed Thowfeek reports on the advantages of the Sampson equation for estimating low-density lipoprotein cholesterol. This recent development is increasingly recommended, and is an important learning point for trainees in clinical biochemistry.

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