The first monthly case report session follows the treatment of a patient with severe hypercholesterolemia and cardiovascular complications from the age of 7 to 41.

The second case report session covers 3 different cases providing key take-home messages that include: know what “lipaemia” means; if lipids are not ordered, ask the lab to add these on; be aware of what your local lab can offer to give you other biochemistry results when a sample is lipaemic; be aware of pseudohyponatraemia, how to identify it, and the causes of it; be aware of the causes of high triglycerides; and involve medical, endocrine, or lab teams in care if not already involved.

The third case report session explores the complex case of a 3-year-old girl with signs of Cushing’s syndrome, including rapid weight gain, hirsutism, central obesity, and hypertension. Investigations showed elevated cortisol and ACTH levels, abnormal suppression/stimulation tests, and inconclusive imaging. Despite no clear adenoma, the pituitary gland was removed, followed by hormone replacement. After initial improvement, the disease relapsed and eventually led to bilateral adrenalectomy. The case highlights the challenges in diagnosing and managing cyclical Cushing’s disease in children.

The fourth case report session provides an overview of the causes of infertility followed by a discussion of the endocrine and other biochemical investigations used in their diagnosis.

The fifth case report session is of a 9 year old girl presenting with hypernatraemia, excessive thirst and polyuria. A water deprivation test is diagnostic of Diabetes Insipidus. MRI and CT imaging of the brain reveals an adenoma on the pituitary gland which results in loss of pituitary function and visual field abnormalities. The main themes of the discussion will be sodium homeostasis, the investigation of polyuria and pituitary function testing.

This sixth case report session focuses on real cases, which illustrates the breath of the metabolic effects of cancer.

The seventh case report session provides an insights into how genomic technologies are becoming embedded in practice in England, presenting some strategic and clinical examples. The presentation from Dr Kenneth Langlands (Assistant Professor in Genomic Medicine, the University of Cambridge, UK) will give an overview of applications, discuss some of the challenges and strengths of these approaches, and highlight the reality that the practice and integration of genomic technologies into care pathways is very complex, with regional variations and international differences.

The eighth case report session explores 4 different patient cases, diabetic ketoacidosis, the risk factors of ketoacidosis, distinguishing type 1 from type 2 and more

The ninth case report session looks at a 42-year-old woman with palpitations, elevated thyroid hormones and a normal TSH. Further biochemical, immunological, genetic and radiological investigations suggested a pituitary micro-adenoma or resistance to thyroid hormone action (Refetoff syndrome). The differential diagnosis and further management are discussed and learning points on resistance to thyroid hormones are identified. Epidemiological data on thyroid disease in Africa is shown, and interpretative comments for reporting of results are considered.

Dr Ojo Moses, Consultant Psychiatrist and Head of Drug Use Disorders Treatment and Rehabilitation unit, Federal Psychiatric hospital Yaba, Nigeria

This webinar highlights different models of Drug of Abuse (DOA) testing, distinguishing between therapeutic and forensic indications. It reviews the methodologies of DOA testing, discussing their strengths, limitations, and potential interferences.

Dr Adeyinka, Professor of Chemical Pathology at the University of Ilorin, Nigeria

During the second quarterly webinar, tumour markers are described with their uses and applications in clinical practice, critically discussed drawing on the latest guidelines and evidence available. In the United Kingdom there is screening programme for colorectal cancer using faecal haemoglobin testing (FIT). The FIT testing program is an excellent model for a cancer screening service and this is also described

During this third quarterly webinar, Dr Kamaljit Kaur Chatha, Consultant Clinical Scientist, discusses her experience of working with artificial intelligence at the bowel cancer screening hub in the West Midlands and endeavoring to apply that into a laboratory practice. The talk also poses questions about what the profession needs to be doing around AI, and the answers that need to be developed to the questions that are raised during the discussion.

In the outcomes of this video, you will understand the relationship between the climate emergency and public health. Learn about the role of the clinical laboratory in the sustainability agenda. Gain knowledge of potential changes in practice to achieve a greener way of working. Speaker: Sheri Scott, Principal Lecturer and Higher Specialist Biomedical Scientist.

Learn how the Medical Training Initiative (MTI) Scheme works, the eligibility criteria, and how it fits into the broader context of GMC registration routes. The many benefits of participating in the MTI scheme, including access to high-quality training, professional development opportunities, and the chance to enhance your skills within the NHS are also highlighted. Speaker: Giles Hanratty, RCPath International Education Officer.

This video provides an overview from entry requirements and programme structure to the different phases of training, including theoretical, practical, and clinical components. As well as the research component, examinations and assessments, and highlights some accredited training institutions. Finally, some of the key challenges and opportunities. Speaker: Professor Tahir Pillay, Clinical Director of International Activities, Royal College of Pathologists.

Learn about the history of postgraduate medical training in Nigeria explaining what it is, and the role chemical pathologists play in healthcare. Drawing from personal experience, the speaker shares what it’s like to practice as a chemical pathologist in Nigeria. The talk also explores the common challenges faced by chemical pathologists working in low-resource settings. Speaker: Dr Sylvester Idogun, Consultant Chemical Pathologist, University Of Benin Teaching Hospital