Charu is a Consultant Clinical Immunologist at the Royal Infirmary of Edinburgh. She leads the SE Scotland regional clinical service for patients with Primary Immune Deficiencies and leads the Immunology diagnostic laboratory within NHS Lothian Laboratory Medicine. 

Charu has an active interest in teaching medical postgraduates and undergraduates, both in medicine and in biomedical sciences programmes at the University of Edinburgh. She co-led the setting up of the Scottish higher medical specialist training programme in Immunology, and is the Training Programme Director (NES) for the programme. She is Associate Postgraduate Dean for Equity, Diversity and Inclusivity in Scotland Deanery, NES.

Sian is a Consultant Clinical Scientist with over 34 years’ experience in genomic medicine at the All Wales Medical Genomics Service (AWMGS), where she most recently served as Laboratory Director. She has played a pivotal role in shaping and leading the development of genomic diagnostic services across Wales, championing innovation and fostering strategic collaboration throughout her career. Alongside her clinical leadership, Sian is an Honorary Senior Research Fellow at Cardiff University. She is also Co-Lead of the multi-award-winning QuicDNA project and the implementation of the new QuicDNA Max programme, reflecting her sustained commitment to excellence, innovation, and patient-centred genomic diagnostics.

Professor Roxburgh graduated from medical school at the University of Glasgow in 2003 and became a member of the Royal College of Physicians in 2006.  She trained in medical oncology in the West of Scotland Medical Oncology training programme and gained her certificate of completion of training in 2015. During medical oncology training she was awarded a Cancer Research UK Clinical Training Fellowship at the Beatson Institute of Cancer Research, where she completed her PhD studies investigated strategies to manipulate the TP53 pathway for cancer therapy.

In 2015 she was awarded the Davies Foundation Travelling Fellowship and travelled to New York to undertake a 1-year fellowship as a clinical scientist in the Roche Translational and Clinical Research Centre. She is now Professor of Experimental Cancer Medicine/ honorary consultant medical oncologist in the University of Glasgow and the Beatson West of Scotland Cancer Centre.  Her areas of specialist expertise are in the treatment of women with ovarian cancer, development of novel cancer therapies, precision oncology and ovarian cancer translation research.  She leads the IMAGINE clinical study, which is a feasibility study aiming to obtain comprehensive somatic genetic testing in a clinically useful timeframe, to support the delivery of personalised experimental cancer therapy.  She is chair of the IMAGINE Molecular tumour board, precision lead for Glasgow Experimental Cancer Medicines Centre and Lead Clinician for cancer genetics in the Scottish Strategic Network for Genomic Medicine.  Professor Roxburgh is a member of the Scottish Gynaecological Cancer Trials Group, European Gynaecologic Oncological Trials, the Gynaecological Cancer Inter-Group and Glasgow lead for the CRUK Scotland centre, ovarian cancer theme.  She is also Chief Investigator of the PArp Inhibitor Resistance (PAIRS), multi-centre, sample collection study which aims to define the mechanisms of PARP inhibitor resistance in patients with high grade epithelial ovarian cancer.