The Part 1 comprises a single paper of 125 multiple choice questions (MCQs) in single best answer format set in broad topic areas aligned with the Curriculum:

• Laboratory management competencies
• Analytical techniques and instrumentation
• Analytical methodology
• The chemical pathology of disease – biochemical basis
• The chemical pathology of disease – diagnosis and principles of management
• The chemical pathology basis of metabolic medicine

Approximately 25% of questions in any one examination will be knowledge based and 75% will concern the application of knowledge. The pass mark for the paper will be set by an objective procedure by an independently-chaired standard setting group where individual questions are reviewed to create a minimum standard using a modified Angoff process. 

Part 2 Module 1

Paper 1

This is a 3 hour objective structured practical examination (OSPE) where candidates are required to answer a series of 19 questions using a selection of material provided whether in paper format or as images/tables on an iPad. The selection of material will include:

• analytical outputs (e.g. electrophoretic strips, chromatography scans)
• clinical scenarios (e.g. sample requirements, investigation protocol questions)
• quality control and/or external quality assurance data
• analytical, physiological or pharmacological calculations
• One question will test communication skills using responses made in writing.

Candidates are given approximately 9 minutes per question with an additional 9 minutes at the end. This makes a total of 3 hours. Candidates can attempt the questions in any order and can decide how much time they wish to spend on specific questions within the 3 hour time window. Each question is marked out of 20, making a total of 380 marks, which is then proportionally reduced to give an overall percentage mark.

Paper 2

This is a 3 hour written practical which tests the candidate’s ability to address an analytical issue. This multi-part paper may test the ability of candidates to plan an experiment, record results, analyse and present raw data, draw appropriate conclusions and produce an action plan or give recommendations. The paper is marked on the basis of the written work produced and a total of 3 hours is allocated. The whole output is marked using the closed marking system, which is then converted to a percentage equivalent mark. Percentage marks are then combined from papers 1 and 2 to give a single percentage mark for the part 2 module 1 exam. 60% of marks come from paper 1 and 40% from paper 2.

NB there will be no old style wet practical using analysers, spectrophotometers, POCT equipment or samples. Candidates will not therefore require lab coats, pipettes, gloves, but should bring appropriate calculators, rulers, pencil and pens.

Paper 3 is a 3 hour written paper in which candidates are required to interpret clinical cases and critically appraise journal articles. In the clinical cases section candidates are given six questions comprising a brief history and laboratory results and are asked to describe and interpret them. In the journal article evaluation section candidates are provided with 2 journal articles, on which they are asked to answer questions that test their critical reading and appraisal skills and their understanding of experimental methods and statistical techniques. 

The Oral examination comprises 2 sections, each with a pair of examiners. In the first, candidates are given 2 questions, one on a managerial topic and the other on either a clinical problem (for medically-qualified candidates) or analytical issue (for scientifically-qualified candidates). Candidates are allowed 30 minutes before the oral examination to review these questions and prepare their answers to them. The second section comprises 4 questions covering patient and laboratory safety and 2 more clinical problems; candidates are not allowed to review the questions in this section before the oral. 

Candidates intending to submit a dissertation must obtain agreement for their project proposal from the College. It is advisable to submit the project proposal well in advance of starting the project in case it is not deemed suitable or requires modification. Failure to submit a proposal or make any required amendments will mean that the dissertation will not be accepted. Candidates are recommended to begin to plan their project and submit a project proposal as soon as possible after entering higher specialist training or equivalent, and before completion of the Part 1 examinations.

In practice the project proposal will usually be submitted as soon as candidates have passed the Part 1 examination, but applications will be accepted at any time after candidates have submitted their application to sit Part 1. The dissertation itself must be submitted after passing the Part 1 examination.

Candidates wishing to submit evidence of a research degree or published papers are advised to do so as soon as they have submitted their application for the Part 1 examination to ensure that, should these not be acceptable, there is sufficient time to undertake a dissertation.

For further guidance, please see the section on ‘Part 2 Written Projects Guidance’ in the Regulations and Guidelines – College examinations for Membership and Diplomas (see the Examinations section of the College website, www.rcpath.org/exams).